The third reaction involved intermediate XVII undergoing acylation using acetyl chloride.
2.
Can I ask why the acetyl chloride is so necessary?
3.
It can be formed by reacting chlorine with acetyl chloride or acetaldehyde in the presence of activated charcoal.
4.
"' Acetyl chloride "', CH 3 COCl is an acid chloride derived from acetic acid.
5.
The OH group is the main site of reaction, as illustrated by the conversion of acetic acid to acetyl chloride.
6.
A few halocarbons, including acid halides like acetyl chloride, are highly reactive; these are rarely found outside chemical processing.
7.
Benzylamine reacts with acetyl chloride to form " N "-benzylacetamide, an exemplar of the Schotten Baumann reaction first described in the 1880s.
8.
A less corrosive compound of salicylic acid, acetylsalicylic acid, produced by reacting sodium salicylate with acetyl chloride, was developed from 1897 by Felix Hoffmann and Arthur Eichengr�n.
9.
Aspirin ( acetylsalicylic acid or ASA ) can be prepared by the esterification of the phenolic hydroxyl group of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride.
10.
In the course of his work on the synthesis and properties of various acid anhydrides, he mixed acetyl chloride with a sodium salt of salicylic acid ( sodium salicylate ).
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